Product Testing Services
Ensuring Quality, Consistency, and Compliance Across the Product Lifecycle
Reliable analytical testing is essential to confirming product quality, batch-to-batch consistency, regulatory compliance, and real-world performance, especially for semi-solid and non-sterile liquid pharmaceuticals. CPL provides a fully integrated suite of GMP product testing services tailored to the complex requirements of topical drug products, including ointments, gels, suspensions, solutions, and nasal sprays. With FDA- and Health Canada-registered laboratories on-site, CPL delivers fast turnaround, consistent quality, and continuous analytical support from early development through commercial manufacturing.
Trusted GMP Product Testing for Semi-Solid and Non-Sterile Liquid Drug Products
CPL’s quality control and analytical laboratories perform a full range of release, stability, and performance testing required to support clinical batch manufacturing, registration campaign, process validation, tech transfer, and ongoing commercial supply. Our QC operation, supported by analytical chemists, microbiologists, stability specialists, and performance testing experts, ensures that every test method, specification, and data package aligns with global regulatory expectations.
Product Testing Core Expertise
Semi-Solid Drug Products
- Assay and related substances
- Content uniformity and homogeneity
- Viscosity, rheology, and texture analysis
- Microstructure and particle-size evaluation
- Preservative effectiveness
- Microbiological testing
- IVRT/IVPT performance data integration
- Ongoing in-use and storage stability
Semi-Solid Drug Products
- Assay and related substances
- Content uniformity and homogeneity
- Viscosity, rheology, and texture analysis
- Microstructure and particle-size evaluation
- Preservative effectiveness
- Microbiological testing
- IVRT/IVPT performance data integration
- Ongoing in-use and storage stability
Non-Sterile Liquid Drug Products
- Assay, impurity, and degradant profiling
- Zeta potential for suspensions
- pH, viscosity, density, appearance
- Preservative and microbial control testing
- Nasal spray pump performance
- Dose delivery and uniformity
- Container closure system integrity testing
- Stability studies aligned with ICH guidelines
Non-Sterile Liquid Drug Products
- Assay, impurity, and degradant profiling
- Zeta potential for suspensions
- pH, viscosity, density, appearance
- Preservative and microbial control testing
- Nasal spray pump performance
- Dose delivery and uniformity
- Container closure system integrity testing
- Stability studies aligned with ICH guidelines
Optimized Analytical Method Meets Validation Requirements
Dedicated to Excellence
from Molecule to Commercialization
CPL supports programs from early-phase through commercial launch, combining preformulation insight, robust semi-solid and non-sterile liquid development, scalable process design, and clinical and commercial manufacturing.
Pharmaceutical Development Services
Pharmaceutical Development Services
Comprehensive expertise that turns molecules into scalable, compliant, market‑ready semi-solid and non-sterile therapies.
Analytical & Product Testing
Analytical & Product Testing
Robust analytics power confident development and manufacture of topical and non-sterile liquid products.
Clinical & Commercial Manufacturing
Clinical & Commercial Manufacturing
More than three decades of GMP manufacturing experience from clinical supply through commercialization.
Packaging, Labeling & Serialization
Packaging, Labeling & Serialization
Integrated packaging, serialization, and aggregation ensure compliant, continuous commercial supply.
Semi-Solid & Non-Sterile Liquid Expertise
Semi-Solid & Non-Sterile Liquid Expertise
Pure-play CDMO for semi-solids and non-sterile liquids, with advanced micro encapsulation capabilities.
Unique Product Handling Experience
Unique Product Handling Experience
Infrastructure and expertise to manage complex, higher-risk semi-solid and non-sterile liquid products.
FAQs
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CPL offers comprehensive product testing for semi-solid and non-sterile liquid formulations, including release testing, stability testing, degradation profiling, elemental impurities testing, residual solvents testing, water determination, dissolution testing, microbiology, preservative efficacy testing, and more. We support topical products such as ointments, creams, gels, lotions, and non-sterile liquid formulations, including suspensions, solutions, and nasal sprays, ensuring compliance with leading pharmacopeias and ICH requirements.
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For semi-solid dosage form manufacturing, CPL provides in vitro release testing (IVRT) per USP <1724> and in vitro permeation testing (IVPT) using Franz diffusion cells. These studies characterize drug release, skin absorption, and dermal penetration, support topical formulation development, and help address topical drug bioequivalence requirements, especially for generic and OTC development and manufacturing programs.
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CPL runs ICH-aligned stability programs (long-term, intermediate, and accelerated) for semi-solids and non-sterile liquids, monitoring CQAs such as potency, degradation products, viscosity, pH, and microbiological quality. We also evaluate container closure systems for tubes, bottles, foil sachets, and nasal spray devices, looking at compatibility, closure integrity, and in-use performance to support product quality and regulatory submissions.
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CPL integrates analytical development services, analytical method validation, and product testing to fully support clinical batch manufacturing, registration batch manufacturing, and commercial manufacturing pharma programs. Our validated methods and GMP testing underpin scale-up, technology transfer, and ongoing pharmaceutical process validation, reducing batch failures, ensuring consistent product performance, and providing robust data packages for Health Canada, FDA, EMA, and other leading regulators.
Commitment.
Partnership. Legacy.
Leverage CPL’s 35 years of expertise in non-sterile liquids and semi-solids to ensure your program's success. We’ll support your product from molecule to market, or step in at any stage of its product lifecycle.
